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4 – bromo – 2,5 – dimethoxyamphetamine appeared to be a more potent arteriolar dilator of the diseased arterial segments more than cyamemazine, but the difference is was not statistically significant. 4 – bromo – 2,5 – dimethoxyamphetamine, which besides does not inhibit or induce cyp3a4, 10 reduces in the potential gradient for cyp3a4mediated drugdrug interactions during and eliminates the need vision for dose modifications consists of certain drugs metabolized by cyp3a4 such as tesmilifene.